University Lecturer in Bioengineering
Academic Division: Mechanics, Materials and Design
Research group: Biomechanics
Telephone: +44 1223 7 48559
Shery Huang's group 'Biointerface', is driven by translational bioengineering research, focusing on 3D bioprinting/ biomicrofabrication, and developing biomimetic organ-on-chips for high throughput drug testing.
Living tissues are intricate ensembles of multiple cell types embedded in a complex, but well-defined extracellular matrix (ECM) of topographical and adhesive features ranging from nanometres to micrometres. Cell ladened ECMs act like units of reaction centres and information hubs. Corporation between these small units lead to a hierarchical structure (i.e. a human body) achieving homeostasis (balance).
We combine nanotechnology and new material fabrication techniques to construct the defined biochemical and physical inputs of an ECM scaffold, and to recapitulate the key attributes of a 'niche' unit. Our research is highly multi-disciplinary in nature, crossing fields of engineering, biology, chemistry, polymer physics and computer science. We aim to translate our scientific findings into exploring a new generation of tissue engineering constructs for personalised therapy, at affordable costs; and to provide new solutions for disease monitoring, drug testing, and better patient healthcare.
Selected research news:
- Near-field electrospinning; low-voltage electrospinning writing
- Bioelectronics via additive manufacturing
- Multi-material deposition of tissue engineering scaffold
- Neural stem cell interface
- Tumor niche models
Projects are available in the following areas. Please contact me to discuss project details.
- Biofabrication (3D printing, multi-material deposition, bioelectronics)
- Computational simulation on cell-material interaction
- In vitro cancer metastasis model
- Neural stem cell interface
Organ-on-chips as pathology models
Soft tissue engineering
Biofabrication for cell patterning, tissue scaffolds and bioelectronics
Director of Studies in Engineering, Homerton College
I completed my MEng degree in Materials Science and Engineering from Imperial College London in 2007 (1st Class; top of the class for four years). With a Cambridge Gates Scholarship, I then pursued a PhD in Physics at Cambridge, focusing on carbon nanotechnology and experimental soft & biological matters. I was a visiting researcher at Prof Rodney Ruoff's lab at University of Texas at Austin (2008). After graduating from my PhD in 2011, I was awarded an Oppenheimer Fellowship and a Homerton College Junior Research Fellowship. Since Aug 2013, I have started my Lectureship in Bioengineering here at Cambridge. Please see my interview with ''The Meaning of Success: Insights from Women at Cambridge'.
Current group members and their projects
- Natasha Lewis (Research Associate); Nephron on a chip
- Saeed Fathi (Research Fellow - part-time); Cell printing
- Magda Gerigk (PhD student); Biomimetic niche of glioblastoma
- Lizzie Gill (PhD student); Bioprinting of mini tissues
- Ye Liu (PhD student); Organ on a chip model
- Andy Wang (PhD student); Functional fibre printing
- Duo Zhang (PhD student); Organ on a chip model
- Keval Patel (PhD student, NIH-Oxbridge program)
- Iek Lei (PhD student, with Dr Mark Birch); Organ on a chip model
- Lukas Vasadi (MRes in Engineering)
- Juying Shen (Summer exchange from Tsinghua University)
Previous PhD and MRes group members
- Zhaoying Li (viva Sept 2017); Membrane-based biointerface
- Xia Li (viva Feb 2017); Electrojet writing of biointerfaces
- Cristina Bertulli (viva Aug 2016); Transendothelial migration in a microvessel-chip
- Nicholas Piano (MRes)
For latest news update about the Biointerface Group: https://twitter.com/Biointerface_CU