Royal Academy of Engineering / Rosetrees Research Fellowship in Closed-loop neurotechnology systems for neuro-metabolic control - NeuMeC
Academic Division: Electrical Engineering
Email: ag2239@cam.ac.uk
Research interests
Dr Amparo Güemes is a Royal Academy of Engineering and Rosetrees Research Fellow at the Bioelectronics Lab, led by Prof George Malliaras. She leads an independent programme at the interface of neurotechnology, bioelectronics, and metabolic control, developing closed-loop platforms that integrate neural and metabolic sensing with adaptive algorithms. Her interdisciplinary work spans signal processing, modelling, analogue and digital bioelectronics, and electrophysiology, bridging engineering innovation with biological insight to create clinically relevant and translationally impactful solutions.
Dr Güemes’s research focuses on bioelectronic medicine, a field that combines biology and engineering to develop treatments using electrical interfaces to interact with the body’s nervous system. Her projects include pre-clinical and clinical studies employing electrical and metabolic bioelectronics for the brain, vagus nerve, and enteric nervous system to improve glucose control in diabetes and reduce seizure frequency and severity in epilepsy, among others. By integrating ultra-low-power analogue front-end circuits, high-bandwidth digital architectures, and real-time adaptive algorithms, her work aims to enable precise monitoring of biomarkers and dynamic modulation of multiple biological circuits, paving the way for highly personalised therapies for complex chronic illnesses.
Her platforms are designed to be scalable, translational, and adaptable to a range of conditions, empowering patients to manage their health and opening opportunities for innovation and economic growth in healthcare technology. Through her research, Dr Güemes contributes to the global advancement of bioelectronic medicine, helping shift from a medication-centric model toward adaptive, personalised therapies powered by advanced neurotechnology.
Research opportunities
Amparo welcomes PhD applications from candidates interested in advancing closed-loop neurotechnology for chronic metabolic diseases. For inquiries, please reach out via email.
Biography
Dr Güemes received her B.S. in Biomedical Engineering (2016) from the Polytechnic University of Madrid (Madrid, Spain), and her M.S. in Biomedical Engineering (2017) and PhD in Electrical Engineering (2021) from Imperial College London (London, UK), where she was supervised by Prof Pantelis Georgiou. Her PhD research focused on the design of mathematical models of the neural regulation of glucose homeostasis. During her doctoral training, Amparo was a visiting PhD research fellow in the Computational Sensory-Motor Systems Lab led by Prof Ralph Etienne-Cummings at Johns Hopkins University (US), where she gained knowledge on the in vivo impact of neural stimulation on blood glucose fluctuations.
Dr Güemes is author of more than 15 publications and presentations, in highly recognized journals and international conferences, such as the Journal of Neural Engineering and the IEEE Journal of Biomedical and Health Informatics. She has won multiple awards from leading institutions including Imperial College and John Hopkins University, such as the Ash Prize for the best academic performance and the Stella Bagrit Centenary Memorial Prize for the best MSc individual project in her MSc in Neurotechnology in Imperial College London, and received the 3rd Prize in the prestigious Spanish National End of Degree Excellence Awards in 2020. She has also been recipient of the Rafael del Pino Felowship to pursue her master and PhD at Imperial College London. In 2021 Amparo was awarded the prestigious 1851 Research Fellowship by the Royal Commission for the Exhibition of 1851 to continue her research as a postdoctoral researcher for three years at the University of Cambridge. In 2023 Amparo's work has recognized with the Engineering Award from the L’Oréal-UNESCO UK and Ireland For Women in Science Rising Talent Programme, which encourages the contribution of women pursuing their research careers. She has recently been a recipient of the Beloe Fellowship and the Royal Academy of Engineering and the Rosetrees Foundation Research fellowships to support her work as a group leader at the Bioelectronics Lab.